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Autonomic changes in ME/CFS are likely to cause an overall effect of vasoconstriction and resultant hypoperfusion (58), which is central to the pathology of ME/CFS (183) ( Figure 8 )

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[61] recently described increased levels of isoprostanes in patients with GDM, thus adding more information to what has already been published by Walsh [62], who had demonstrated higher levels of isoprostanes in preeclamptic placentas

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